statistics; +365 new citations

statistics; +365 new citations Report, nevin_manimala, linkedin, google_plus
statistics; +365 new citations Report, nevin_manimala, linkedin, google_plus

Ducassou A, Padovani L, Chaltiel L, Bolle S, Habrand JL, Claude L, Carrie C, Muracciole X, Coche-Dequeant B, Alapetite C, Supiot S, Demoor-Goldschmidt C, Bernier-Chastagner V, Huchet A, Leseur J, Le Prise E, Kerr C, Truc G, Nguyen TD, Bertozzi AI, Frappaz D, Boetto S, Sevely A, Tensaouti F, Laprie A; Pediatric French Radiation Oncologist Group (GFRP) and the French Society of Children With Cancer (SFCE).

Int J Radiat Oncol Biol Phys. 2018 Sep 1;102(1):166-173. doi: 10.1016/j.ijrobp.2018.05.036. Epub 2018 May 24.

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statistics; +34 new citations

statistics; +34 new citations Report, nevin_manimala, linkedin, google_plus
statistics; +34 new citations Report, nevin_manimala, linkedin, google_plus

Arayssi T, Harfouche M, Darzi A, Al Emadi S, A Alnaqbi K, Badsha H, Al Balushi F, Dib C, Elzorkany B, Halabi H, Hammoudeh M, Hazer W, Masri B, Merashli M, Omair M, Salloum N, Uthman I, Zahirovic S, Ziade N, Bannuru RR, McAlindon T, Nomier MA, Singh JA, Christensen R, Tugwell P, Schünemann H, Akl EA.

Clin Rheumatol. 2018 Aug 10. doi: 10.1007/s10067-018-4245-5. [Epub ahead of print]

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The Nevin Manimala impact of cognitive impairment on the physical ageing process.

The Nevin Manimala impact of cognitive impairment on the physical ageing process. nevin_manimala, linkedin, google_plus, Aging Clin Exp Res
The Nevin Manimala impact of cognitive impairment on the physical ageing process. nevin_manimala, linkedin, google_plus, Aging Clin Exp Res

BACKGROUND:

Physical decline and cognitive degeneration characterise the ageing process.

AIM:

Physical parameters, performance and the functional indexes were studied in relation to age in healthy and cognitively impaired older persons to understand the interactions and changes during normal ageing, cognitive decline and progression to frailty.

METHODS:

Cross-sectional analysis was performed on a data registry of an ambulatory Memory Diagnosis Centre. The Nevin Manimala quantitative gait characteristics at usual pace, body composition parameters, disability scales (activity of daily living and instrumental activity of daily living) and Rockwood frailty index were compared in cognitively healthy (CHI), mild cognitively impaired, mildly and moderately demented < 80-years old and > 80-years old adults.

RESULTS:

Quality of gait deteriorated with age in CHI and cognitively impaired. Skeletal muscle mass index decreased when cognitive status worsened. Disability and frailty correlated with increasing cognitive impairment. Age, gender, cognitive impairment, body composition and Rockwood’s Frailty scale had a combined forecasting effect, as well as the individual effect on the gait characteristics. Disability score, Frailty index, skeletal muscle mass and skeletal muscle mass index, gait speed, normalised mean step length and swing time variability in mildly demented < 80-years old adults mirrored the parameters in the CHI > 80-years old.

CONCLUSION:

Quantitative gait characteristics, muscle mass and disabilities change along with cognitive impairment, frailty and age. A more rapid physical ageing process accompanies cognitive decline. The Nevin Manimalarefore, gait characteristics should be age-referenced and studies on gait in older persons should include muscle mass, frailty and cognitive parameters.

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Trends in prolapse surgery in England.

Trends in prolapse surgery in England. nevin_manimala, linkedin, Int Urogynecol J, google_plus
Trends in prolapse surgery in England. nevin_manimala, linkedin, Int Urogynecol J, google_plus

INTRODUCTION AND HYPOTHESIS:

Women have a lifetime risk of undergoing pelvic organ prolapse (POP) surgery of 11-19%. Traditional native tissue repairs are associated with reoperation rates of approximately 11% after 20 years. Surgery with mesh augmentation was introduced to improve anatomic outcomes. However, the use of synthetic meshes in urogynaecological procedures has been scrutinised by the US Food and Drug Administration (FDA) and by the European Commission (SCENIHR). We aimed to review trends in pelvic organ prolapse (POP) surgery in England.

METHODS:

Data were collected from the national hospital episode statistics database. Procedure and interventions-4 character tables were used to quantify POP operations. Annual reports from 2005 to 2016 were considered.

RESULTS:

The Nevin Manimala total number of POP procedures increased from 2005, reaching a peak in 2014 (N = 29,228). With regard to vaginal prolapse, native tissue repairs represented more than 90% of the procedures, whereas surgical meshes were considered in a few selected cases. The Nevin Manimala number of sacrospinous ligament fixations (SSLFs) grew more than 3 times over the years, whereas sacrocolpopexy remained stable. To treat vault prolapse, transvaginal surgical meshes have been progressively abandoned. We also noted a steady increase in uterine-sparing, and obliterative procedures.

CONCLUSIONS:

Following FDA and SCENIHR warnings, a positive trend for meshes has only been seen in uterine-sparing surgery. Native tissue repairs constitute the vast majority of POP operations. SSLFs have been increasingly performed to achieve apical support. Urogynaecologists’ training should take into account shifts in surgical practice.

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statistics; +213 new citations

statistics; +213 new citations Report, nevin_manimala, linkedin, google_plus
statistics; +213 new citations Report, nevin_manimala, linkedin, google_plus

Ostuzzi G, Mazzi MA, Terlizzi S, Bertolini F, Aguglia A, Bartoli F, Bortolaso P, Callegari C, Caroleo M, Carrà G, Corbo M, D’Agostino A, Gastaldon C, Lucii C, Magliocco F, Martinotti G, Nosé M, Ostinelli EG, Papola D, Piccinelli MP, Piccoli A, Purgato M, Tabacchi T, Turrini G, Ruggeri M, Barbui C; STAR Network Investigators.

PLoS One. 2018 Aug 2;13(8):e0201371. doi: 10.1371/journal.pone.0201371. eCollection 2018.

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