J Cosmet Dermatol. 2021 Mar 8. doi: 10.1111/jocd.14048. Online ahead of print.
ABSTRACT
AIM: Alopecia areata (AA) is an inflammatory condition that causes regional shedding without scarring on the hair or eyebrows, eyelashes and beard. In studies conducted, it has been concluded that platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR) and mean platelet volume (MPV) are significant indicators of systemic inflammation in various diseases. In the present study, our aim is to examine these parameters in AA patients and to investigate their relationship with the disease.
MATERIALS AND METHODS: 135 AA patients and 135 healthy controls who did not have any systemic, inflammatory, infectious or autoimmune diseases were included in this study. Demographic characteristics and complete blood count (CBC) results were analysed retrospectively and recorded and statistical analysis was performed.
RESULTS: PLR, NLR and MPV values were not differ between AA patients and the control group.
CONCLUSION: It can be concluded that PLR, NLR and MPV values are not convenient parameters to show inflammatory response in AA.
PMID:33682292 | DOI:10.1111/jocd.14048
