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Predicting survival after liver transplant: A noble pursuit or a fool’s errand?

Liver Transpl. 2021 Mar 26. doi: 10.1002/lt.26057. Online ahead of print.

ABSTRACT

Organ shortage continues to limit our ability to provide transplant to all in need of liver transplantation. The current urgency-based system is based on the laboratory MELD-Na score, which efficiently and effectively rank orders patients by their estimated risk for 90-day waitlist mortality, with a c-statistic of 0.88.1 MELD-Na is agnostic to factors such as age, etiology of liver disease, and co-morbidity, as well as one’s expected post-transplant survival. Transplant centers are entrusted, according to the Final Rule, to ensure that candidates meet a minimal threshold of utility where liver transplant would benefit the patient.

PMID:33773023 | DOI:10.1002/lt.26057

By Nevin Manimala

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