J Indian Soc Pedod Prev Dent. 2021 Jan-Mar;39(1):36-41. doi: 10.4103/jisppd.jisppd_527_20.
ABSTRACT
BACKGROUND: Propylthiouracil (PROP) (a medicated tool) and hormonal fingerprint (second to fourth digits [2D:4D]) ratio can be used for detection of caries which is most prevalent oral health disease.
AIM: This study aims to determine the role of genetic taste sensitivity and hormonal fingerprint (2D:4D ratio) on caries risk susceptibility.
MATERIALS AND METHODS: The present study was an observational and cross-sectional study. It was conducted on 570 children aged 6-12 years. PROP sensitivity test was done by PROP impregnated filter paper strips and subjects were divided accordingly into supertasters, medium-tasters, and nontasters. 2D:4D ratio was obtained by measuring length ratio of index to ring finger using Vernier caliper. Dietary preferences of the subjects were recorded. The evaluation of decayed, missing, and filled teeth/deft indices was done.
STATISTICAL ANALYSIS: Intergroup comparisons were performed using One-way ANOVA test, independent t-test and Chi-square test at 5% significance level.
RESULTS: Positive correlation between nontasters, low digit ratio, sweet likers, and high caries index was found with a high significant difference.
CONCLUSION: Genetic taste sensitivity and hormonal fingerprint (biological marker) can be used for detection of caries as the present research confirmed impact of hormones on taste perception.
PMID:33885385 | DOI:10.4103/jisppd.jisppd_527_20