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Vitamin D Levels in Neonates With and Without Seizures: A Single Center Cross-Sectional Study

Indian Pediatr. 2021 May 20:S097475591600330. Online ahead of print.

ABSTRACT

OBJECTIVE: To study the serum vitamin D levels in neonatal seizures and vitamin D status of the mothers whose babies had vitamin D deficiency.

METHODS: For this case-control study, vitamin D levels were studied in term and late preterm neonates admitted to NICU with seizures in a tertiary care center in South India. Controls were term and late preterm healthy neonates admitted in the postnatal ward with the mothers in the same center.

RESULT: 30 cases and 30 controls were enrolled. The mean (SD) serum vitamin D was 19.33 (7.76) ng/mL among cases and 16.83 (6.74) ng/mL among controls (P=0.18). We tested maternal vitamin D levels in babies with seizures and low vitamin D levels. The mean (SD) serum vitamin D level among these mothers (n=11) was 13.25 (6.17) ng/mL.

CONCLUSION: There was no statistically significant association between serum vitamin D levels and seizures among neonates in our study. However, we found low vitamin D levels in lactating mothers and newborn population of this region.

PMID:34016803

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