Int J Clin Pract. 2021 May 30:e14259. doi: 10.1111/ijcp.14259. Online ahead of print.
ABSTRACT
OBJECTIVE: This study aimed to correlate the radiographic findings of the coronavirus disease 2019 (COVID-19) positive children with their clinical and laboratory findings, discuss the frequency and necessity of chest computed tomography (CT) used for the radiological imaging in pediatric patients with COVID-19 infection.
MATERIALS AND METHODS: Sixty-nine pediatric inpatient cases were retrospectively analyzed using their clinical, laboratory, and imaging features. The National Public Health Guide was used in the diagnosis and treatment of pediatric patients. COVID-19 infections for all patients were confirmed by the COVID-19 nucleic acid test using a pharyngeal swab.
RESULTS: The median age of the patients was 11 [3-15] years. The most common clinical symptoms were fever (40,6%) and cough (33,3%). When the laboratory findings of patients were examined, the median WBC count was 5.8/mm3 [4.8-8.05/mm3 ], median lymphocyte count was 2.3/mm3 [1.7-3.55/mm3 ], and median C-reactive protein (CRP) level was 2.3/mm3 [1-2.1/mm3 ]. All patients had chest radiographs (CRXs), while only 44.9% of the patients underwent a chest CT. The 8.7% of CXRs and 12.8% of chest CT findings were found as pathological. Ground-glass opacity was the most frequent finding. In the tomography group, the count of lymphocytes was lower, and creatine kinase (CK) and lactate dehydrogenase (LDH) levels were significantly higher. The patients with pathological tomography findings demonstrated no statistically significant difference in lymphocyte count, and CK and LDH levels; however, their CRP value was significantly higher.
CONCLUSION: In this study, it is emphasized that chest CT should be requested by considering the underlying diseases and severity of clinical findings in pediatric patients. In this way, unnecessary chest CT could be prevented in the pediatric population.
PMID:34053160 | DOI:10.1111/ijcp.14259
