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Effectiveness and usability of mobile health applications to medication adherence for heart failure: a systematic review protocol

JBI Evid Synth. 2021 Jun 1. doi: 10.11124/JBIES-20-00399. Online ahead of print.

ABSTRACT

OBJECTIVE: This review will assess the effectiveness and usability of mobile health applications to improve medication adherence in patients with heart failure.

INTRODUCTION: Inadequate medication adherence by heart failure patients is a major cause of negative clinical outcomes, high rates of hospital readmissions, and death, thus increasing the costs to patients and the health care system. Several studies have shown that the use of mobile health applications improves self-care by heart failure patients, including medication adherence. Therefore, gathering evidence on these studies will help researchers and clinicians understand the impact of such interventions on patient care.

INCLUSION CRITERIA: Eligible studies will evaluate medication adherence and include participants aged ≥18 years diagnosed with heart failure who are using app-based (software) interventions. Experimental and observational studies will be included. We will exclude studies with interventions that used mobile applications without functionality to assist the user in organizing and taking their medications.

METHODS: Articles published to the present day, without restrictions of language, will be selected from Embase, MEDLINE, LILACS, Scopus, Web of Science, CINAHL, and Cochrane Library. Two independent reviewers will perform article screening, assessment of methodological quality, and data extraction using JBI assessment and extraction instruments. Discrepancies will be solved by consensus and a third reviewer will be consulted if necessary. A narrative synthesis of findings will be presented, and statistical analysis will be used only when appropriate.

SYSTEMATIC REVIEW REGISTRATION NUMBER: PROSPERO CRD42020147816.

PMID:34074907 | DOI:10.11124/JBIES-20-00399

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