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Agreement and repeatability of corneal tomography in healthy eyes using a novel Swept-Source optical coherence tomographer, a rotating Scheimpflug camera and a dual Scheimpflug-Placido system

J Cataract Refract Surg. 2021 Jun 28. doi: 10.1097/j.jcrs.0000000000000734. Online ahead of print.

ABSTRACT

PURPOSE: To investigate the accordance and repeatability of tomographic parameters measured by a novel Swept-Source optical coherence tomographer (SS-OCT, ANTERION), a rotating Scheimpflug camera (RSC, Pentacam) and a dual Scheimpflug-Placido system (DSP, Galilei G6).

SETTING: Department of Ophthalmology of Univ. Hospital Carl Gustav Carus, Dresden, Germany.

DESIGN: Prospective reliability analysis.

METHODS: Thirty randomly selected eyes of 30 healthy participants were enrolled in this study. Normal tomography were ensured by bilaterally evaluating appropriated parameters using RSC. All subjects received three consecutive measurements on each device by the same operator and in the uniform order RSC, SS-OCT and DSP. Anterior (ACP) and posterior (PCP) corneal parameters such as flat and steep keratometry and corneal thickness were analyzed. Repeatability was assessed by using a coefficient of repeatability (CR) and a coefficient of variation (CV). Agreement between RSC and SS-OCT as well as RSC and DSP were shown by Bland-Altman plots (BA).

RESULTS: CR of ACP did not exceed 0.5 D. There were no statistical differences in repeatability of ACP obtained from the three devices (P>0.05). For PCP and corneal thickness there was statistically significant higher repeatability mostly found for SS-OCT as opposed to RSC and DSP (P<0.05). For a wide range of analyzed parameters there were large limits of agreement (95%-LoA) found between the devices.

CONCLUSION: The SS-OCT showed highly repeatable measurements in healthy subjects regarding anterior, posterior and corneal thickness parameters. Repeatability of ACP did not differ between the devices. A mostly wide range of 95%-LoA prevents interchangeability between the devices.

PMID:34224476 | DOI:10.1097/j.jcrs.0000000000000734

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