J Occup Environ Med. 2021 Jul 1. doi: 10.1097/JOM.0000000000002310. Online ahead of print.
ABSTRACT
OBJECTIVE: The aim of this study is to evaluate whether the exposure to a low dose of Nickel could determinate a variation in levels of progesterone in outdoor workers.
MATERIALS AND METHODS: 261 subjects were divided by gender, task, age, seniority and cigarette smoking habit. For each workers was evaluated the dose of blood progesterone and urinary nickel.The statistical analysis was performed.
RESULTS: The Pearson correlation showed a statistically significant correlation between urinary nickel levels and progesterone. The Multiple linear regression showed a significant correlation between progesterone and urinary nickel in the total sample and in the subgroups of smokers and workers with tasks of traffic direction.
CONCLUSIONS: The results of our study suggest that occupational exposure to low doses of nickel present in urban pollution may influence to progesterone levels in outdoor workers.
PMID:34224421 | DOI:10.1097/JOM.0000000000002310
