Categories
Nevin Manimala Statistics

A Misconception About the Hardy-Weinberg Law

Twin Res Hum Genet. 2021 Jul 22:1-3. doi: 10.1017/thg.2021.26. Online ahead of print.

ABSTRACT

The Hardy-Weinberg law of population genetics is usually associated with the notion of random mating of parents. A numerical example for a triallelic autosomal locus shows that an uncountable set of mating combinations can maintain Hardy-Weinberg proportions. Therefore, one cannot infer random mating in a population from the observation of Hardy-Weinberg equilibrium. The mating system which ensures that the genotypic distribution of offspring is the same as that of the parents is specified.

PMID:34291729 | DOI:10.1017/thg.2021.26

By Nevin Manimala

Portfolio Website for Nevin Manimala