J Plast Surg Hand Surg. 2021 Jul 29:1-6. doi: 10.1080/2000656X.2021.1952211. Online ahead of print.
ABSTRACT
BACKGROUND: Near-infrared spectroscopy (NIRS) is widely used to assess flap perfusions by measuring tissue oxygen saturation (StO2). However, the StO2 level for the onset of perfusion failure is still a controversial issue.
AIM: This study proposes a new threshold of StO2 level for detecting the onset of perfusion failure as early as possible to increase flap salvage rates.
METHODS: Twenty patients undergoing flap surgery were included in this study – 13 flaps were implemented to cover defects that occurred due to trauma and 7 flaps to hide imperfections that occurred after cancer treatment. Thirteen flaps were in the lower extremity, six in the mandible, and one in the breast. NIRS was used to measure StO2 in 240 flap regions of the 20 patients to determine flap viability using descriptive statistics.
RESULTS: The mean StO2 values from healthy flap and control regions were obtained as 81.6% ± 0.36 and 82% ± 0.18, respectively. The lowest StO2 value of 77.2% was defined as the onset of a vascular complication at a probability of 99.74% by subtracting three times the standard deviation from the mean StO2 of healthy flaps. Vascular complications were observed from 21 regions in the four flaps with StO2 values lower than 77.2%, but only one was lost.
CONCLUSION: The threshold value for the onset of perfusion failure was a 5% decrease from the expected value, much lower than previously described thresholds that may facilitate the detection of perfusion failure in the early stage and increase salvage rates in flap revisions.
PMID:34323644 | DOI:10.1080/2000656X.2021.1952211