Arthritis Care Res (Hoboken). 2021 Sep 3. doi: 10.1002/acr.24777. Online ahead of print.
ABSTRACT
We thank Dr Lai for their interest in our study (1). While we did not show a statistically significant link between the use of allopurinol and mortality in people with gout, we agree that Allopurinol Hypersensitivity Syndrome (AHS) is the most serious side-effect of allopurinol, particularly in populations with South East Asian ancestry, leading to the recommendation to screen people of South East Asian descent for the HLA-B*5801 allele prior to starting treatment with allopurinol (2,3).
PMID:34477323 | DOI:10.1002/acr.24777
