Parasit Vectors. 2021 Sep 21;14(1):485. doi: 10.1186/s13071-021-04957-2.
ABSTRACT
We read with great interest the article by Yin et al. (Parasit Vectors 14:238, 2021). The authors found that Cryptosporidium infection induced significantly aberrant expression of circular RNA profiles in HCT-8 cells, a finding which has far-reaching implications. However, due to the high number of false positives caused by multiple comparisons, statistical methods for microarray analysis should be carefully selected. Accurate analysis results will provide a convincing basis for subsequent experiments. In addition, we recommend several more appropriate methods in this article.
PMID:34548105 | DOI:10.1186/s13071-021-04957-2
