J Med Virol. 2021 Oct 11. doi: 10.1002/jmv.27384. Online ahead of print.
ABSTRACT
OBJECTIVE: Disparities in outcomes exist in outcomes of COVID19. Little is known about other ethnic minorities in US.
METHODS: We included all COVID-19 positive adult patients (≥18 years) hospitalized between March 1, 2020 and February 5th 2021. We compared in hospital mortality, use of intensive care unit services and inflammatory markers between non-Hispanic whites with non-White/Black Hispanic. Multivariable Cox proportional Hazard models were used to adjust for differences between the two groups.
RESULTS: There were 4059 hospital admissions with COVID-19 in the study period. Of the 3288 White, 789(24%) required ICU admission in comparison to 187 (24.3%) of the 770 Hispanics. Unadjusted mortality was higher in Whites than Hispanics (17.1% versus 10.7%; p<0.001). After adjusting for confounding variables, in-hospital mortality was not statistically different for Whites in comparison to Hispanics (HR 0.96, 95%CI 0.76-1.21, p=0.73). The adjusted rates of ICU transfers were significantly higher in Hispanics (HR 1.34, 95%CI 1.11-1.61, p=0.002). Hispanics had significantly higher CRP, LDH and fibrinogen when compared to Whites.
CONCLUSION: Hispanics as compared to Whites with COVID-19 require higher rates of ICU admission but have a similar mortality. This article is protected by copyright. All rights reserved.
PMID:34633096 | DOI:10.1002/jmv.27384