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A comparison of different methods to calculate the axial length measured by optical biometry

J Cataract Refract Surg. 2021 Sep 20. doi: 10.1097/j.jcrs.0000000000000821. Online ahead of print.

ABSTRACT

PurposeTo compare axial length (AL) measurements in long eyes by two swept-source optical coherence tomography (SS-OCT) biometers, one based on the group refractive index (IOLMaster 700, Zeiss) and the other based on sum of segments (Argos, Movu), and compare these measurements to previously published methods to optimize AL.SettingI.R.C.C.S. – G.B. Bietti Foundation, Rome, ItalyDesignProspective case seriesMethodsAL was measured with both optical biometers in myopic patients (AL > 24.00 mm) and compared to the values obtained with Wang-Koch adjustment, polynomial equations for the Holladay 1 and 2 formulas and Cooke modified AL (CMAL).ResultsIn 102 eyes of 55 subjects, a statistically significant difference (p<0.0001) was found among the 6 AL values. Post-test revealed that Argos measurements (26.90 ±1.61 mm) were significantly lower compared to those provided by all methods (p <0.001) but CMAL, whereas IOLMaster 700 measurements (27.01 ±1.65) were higher (p <0.001). No difference was found between the two Holladay equations. CMAL values did not reveal any difference compared to those of the Argos, but a proportional bias showed that in longer eyes CMAL provided smaller values (p <0.0001, r = -0.7221). AL overestimation by the IOLMaster 700 AL compared to the Argos was higher the longer the eye was (p <0.0001, r = 0.6959, r2 = 0.4842).ConclusionThe SS-OCT optical biometer based on the group refractive index overestimates AL compared to the device using segmented AL. CMAL provides the measurements closest to those of the device using segmented AL.

PMID:34653096 | DOI:10.1097/j.jcrs.0000000000000821

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