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Influence of periapical lesion size on healing outcome following regenerative endodontic procedures: a clinical investigation

Oral Radiol. 2021 Nov 26. doi: 10.1007/s11282-021-00578-8. Online ahead of print.

ABSTRACT

OBJECTIVES: The current study aimed to investigate the influence of the periapical lesion size on healing outcome following Regenerative Endodontic Procedures (REPs) in mature teeth using cone-beam computed tomography (CBCT) and Mimics software.

METHODS: The study included ten mature necrotic maxillary anterior teeth with periapical lesions ≥ 3 CBCT Periapical index score (CBCTPAI). REPs via blood clots were performed for all the teeth. CBCT scans were taken pre and postoperatively after 12 months follow-up periods and transferred to Mimics for volume measurements and comparison. Statistical analysis was performed using the Wilcoxon signed-rank test.

RESULT: All teeth were symptom-free with a statistically significant decrease in the volume of the periapical lesion (P < 0.05) after 12 months except for one case.

CONCLUSION: The study concluded that REPs could be a successful treatment modality for mature necrotic teeth with periapical lesions however the size of the preoperative periapical lesion could affect the outcome of the periapical healing.

TRIAL REGISTRATION: The study was registered in ClinicalTrials.gov (ID: NCT04646538).

PMID:34826060 | DOI:10.1007/s11282-021-00578-8

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