Colorectal Dis. 2022 Jan 17. doi: 10.1111/codi.16054. Online ahead of print.
ABSTRACT
AIM: To determine safety of performing an anastomosis after rectal cancer (RC) resection in patients with a previously treated prostate cancer (PC).
METHODS: Patients with a previously treated PC who underwent rectal resection from 2008 to 2018 were retrospectively included. Outcomes were compared between patients who underwent rectal resection with anastomosis (restorative surgery, RS+ group) and those with a definitive stoma (RS- group). In the RS+ group, anastomotic leak (AL) rates were assessed according to the type of reconstruction.
RESULTS: 126 patients underwent rectal surgery for mid-low RC after a previously PC treated by RT and/or radical prostatectomy. Overall, 80 patients (63%) underwent a RS and 46 patients (37%) underwent rectal surgery with a definitive stoma. There was no statistical difference between the two groups in terms of intraoperative data, except for the type of resection with more multivisceral resection in the RS- group (p<0.01). In the RS+ group, a diverting stoma was performed in 74% of cases. No difference between the two groups in terms of overall morbidity was found. In the RS+ group (n=80), 17 patients (21%) experienced AL. Of these none was observed when delayed coloanal anastomosis was performed (p=0.16). Long-term permanent stoma in the RS+ group was 16% (n=13).
CONCLUSION: Restorative surgery after resection for RC in patients with a previous history of RT and/or radical prostatectomy for PC is safe without additional morbidity. In selected patients for restorative surgery, performing delayed coloanal anastomosis may represent a promising option.
PMID:35038368 | DOI:10.1111/codi.16054
