Clin Oral Implants Res. 2022 Feb 27. doi: 10.1111/clr.13912. Online ahead of print.
ABSTRACT
AIM: To compare the effectiveness of two xenografts for maxillary sinus floor augmentation in terms of clinical, radiographical, histological and molecular outcomes.
MATERIALS AND METHODS: A split-mouth randomized clinical trial was conducted at the University of Granada. Ten consecutive patients in need of bilateral two staged maxillary sinus floor augmentation were included. Each patient received both biomaterials (porcine bone mineral and anorganic bovine bone), which were randomly assigned for bilateral sinus augmentation. The maxillary autogenous bone scraped from the sinus access window was mixed with each xenograft at a 20:80 ratio. After a healing period of 6 months, bone biopsies were collected with a trephine during the implant placement in the regenerated area. Histological, histomorphometrical, immunohistochemical and molecular outcomes were analyzed. Clinical and radiographical data throughout the treatment phases were also evaluated.
RESULTS: The resulting anatomical features were similar between both groups. After six months of graft consolidation, the graft resorption rates were similar between both biomaterials. The histological, histomorphometrical and immunohistochemical results showed no statistical differences between groups.
CONCLUSION: Anorganic bovine bone and porcine bone mineral combined with maxillary autogenous cortical bone show similar biological and radiological features in terms of biomaterial resorption, osteoconduction and osteogenesis when used for maxillary sinus floor augmentation.
PMID:35224778 | DOI:10.1111/clr.13912
