Georgian Med News. 2022 Mar;(324):32-37.
ABSTRACT
The aim of this study was to optimize the diagnosis of postpartum inflammatory complications. 150 puerperas who gave written informed consent to participate in clinical and laboratory studies were divided into two groups: the main group included puerperas with developed postpartum complications (n = 100), the comparison group included puerperas with a physiological course of the postpartum period (n = 50). The data of biochemical blood tests and bacteriological analysis of aspirated vaginal contents under aseptic conditions after childbirth were used as material. Against the background of the development of the inflammatory process in the early postpartum period, a decrease in quantitative indicators of hemoglobin and changes in white blood parameters with an increase in the level of leukocytes to 10.6±0.08×109/l in the main group, against 6.2±0.13×109/l in the control group group (P=0.001). It is important to note the relatively high level of ESR, which in puerperas of the main group was 23.1±0.22 mm/hour, against 8.4±0.16 mm/hour in the control group (P=0.001). Significant distinguishing features between the groups are recorded by the frequency of occurrence in the anamnesis of medical and spontaneous abortions, which were significantly higher in women of the main group (p=0.004). Patients of different groups have statistically significant differences in the somatic history data – in the puerperas of the main group, chronic pyelonephritis and inflammatory diseases of the upper respiratory tract (chronic tonsillitis, sinusitis) were more often diagnosed. Significant deviations also affected the quantitative indicators of lymphocytes (P=0.001). Among past sexually transmitted infections, the development of early puerperal inflammatory complications can be influenced by trichomoniasis (p=0.035), chlamydia (p=0.036), the frequency of which in the main group is quite significant compared to the control. The presence of inflammatory postpartum complications in patients of the main group increases the contamination, possibly also due to a significant increase in the frequency of inoculation of Mycoplasma Hominis (titer≥104) 38.0±4.85%, Ureaplasma urealiticum (titer≥104) – 73.0±4.44% (p<0.05). Comparative analysis showed that the incidence of Staphylococcus spp in patients of the main group was higher in comparison with the control group. A significant difference in patients of the main group with the control group was observed in relation to the frequency of occurrence of Streptococcus spp. Microorganisms of the Enterobacteriaceae family were also frequently sown species.
PMID:35417860
