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LONG-TERM OUTCOMES OF ROBOT-ASSISTED RADICAL THYMECTOMY FOR LARGE THYMOMAS: A PROPENSITY MATCHED ANALYSIS

Int J Med Robot. 2022 Jul 13:e2439. doi: 10.1002/rcs.2439. Online ahead of print.

ABSTRACT

BACKGROUND: The aim of this study was to evaluate the long-term results of robot-assisted (RATS) thymectomy in the treatment of large thymomas, defined as larger than 5 cm.

METHODS: We retrospectively reviewed 106 thymectomies from 2010 to 2020, creating two groups based on the surgical approach (open or RATS) and size. Kaplan-Meier and Cox-regression were used to estimate and identify risk factors of oncological outcomes. To perform a well-balanced analysis, a propensity score matched (PSM) analysis was conducted for large thymomas.

RESULTS: From 2015, we performed 54 RATS thymectomies: 53.7% (n=29) for small and 46.3% (n=25) for large thymomas. Conversions were similar and all patients had a complete resection. The overall (82% vs 92%, p=0.57) and disease-free survival were comparable between RATS and open (92.5% vs 93%, p=0.67), outcomes confirmed after PSM for large thymomas.

CONCLUSIONS: RATS thymectomy could be considered a valid option in selected patients with large thymomas.

PMID:35830541 | DOI:10.1002/rcs.2439

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