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Does using a laser improve outcomes of conventional circumcision in adult and children populations? Results from a systematic review and meta-analysis

Andrology. 2022 Oct 17. doi: 10.1111/andr.13321. Online ahead of print.

ABSTRACT

BACKGROUND: Male circumcision is a well know old surgery, and several recently developed techniques have been scaled up, including the introduction of laser technology, as alternative approaches to overcome morbidity of conventional surgery scalpel/suture method OBJECTIVES: We aimed to perform a systematic review and meta-analysis of studies comparing laser circumcision versus conventional circumcision technique in terms of perioperative outcomes and efficacy (complications, unacceptable appearance, reoperation rate) both in children and adults.

MATERIALS AND METHODS: This review was performed following the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analyses framework. Continuous variables were analyzed using the inverse variance of the mean difference (MD) with a random effect, 95% Confidence Interval (CI), and p-values. The incidence of complications, unacceptable appearance, and reoperation rate were pooled using the Cochran-Mantel-Haenszel Method with the random effect model and reported as Odds Ratio (OR), 95% CI, and p-values. Significance was set at p-value ≤0.05 and 95%CI.

RESULTS: Seven studies were included. In comparison to the conventional circumcision, laser circumcision shoved lower visual analogue score at 24-hour, and 7 days after surgery, a lower rate of overall complication rate (OR 0.33, 95% CI 0.24 – 0.47, p<0.001), scarring (OR 0.09, 95% CI 0.02,0.41, p = 0.002) and unacceptable appearance (OR 0.09, 95% CI 0.05, 0.15, p<0.001). We found no statistically significant difference in surgical time, and incidence of bleeding, infection, wound dehiscence, and reoperation rate.

DISCUSSION AND CONCLUSION: Our review infers that laser-assisted circumcision is certainly a safe and strong contender as the procedure of choice in both children and adult populations. This article is protected by copyright. All rights reserved.

PMID:36251782 | DOI:10.1111/andr.13321

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