Clin Physiol Funct Imaging. 2022 Nov 28. doi: 10.1111/cpf.12803. Online ahead of print.
ABSTRACT
BACKGROUND: Reduced field-of-view DWI could be proved to quantitatively identify thyroid papillary carcinoma and there is no literature regarding the use of T1-mapping to distinguish nodular goiter from thyroid papillary carcinoma.
PURPOSE: To compare T1-mapping with reduced field-of-view DWI in differentiating nodular goiter and thyroid papillary carcinoma.
STUDY TYPE: Prospective study.
POPULATIONS: Ninety-five hospitalized patients with thyroid nodules were were included into the research.
SEQUENCE: All subjects underwent T1WI, T2WI, reduced field-of-view DWI and T1-mapping sequences.
ASSESSMENT: ADC and T1 values of each thyroid nodule were measured respectively. According to pathological results, the thyroid nodules were divided into two groups: Group 1 (nodular goiter) and Group 2 (thyroid papillary carcinoma).
STATISTICAL TESTS: An independent sample t test was used to evaluate the differences of ADC and T1 between two groups. ROC curve was used to analyse the diagnostic efficiency of T1, ADC, Thyroid Imaging Reporting and Data System, T1&ADC.
RESULTS: The T1 and ADC values of nodular goiter were both higher than those of thyroid papillary carcinoma (P < 0.05). The AUC values of T1 & ADC were significantly higher than that of T1 or ADC alone (P < 0.05). The AUC value of T1 & ADC was as same as that of TI-RADS.
CONCLUSION: The combination of T1-mapping and reduced field-of-view DWI could effectively differentiate nodular goiter from thyroid papillary carcinoma. And it has at least the same diagnostic value as the ultrasound based TI-RADS classification. This article is protected by copyright. All rights reserved.
PMID:36440541 | DOI:10.1111/cpf.12803
