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HiCube: Interactive visualization of multiscale and multimodal Hi-C and 3D genome data

Bioinformatics. 2023 Mar 24:btad154. doi: 10.1093/bioinformatics/btad154. Online ahead of print.

ABSTRACT

SUMMARY: HiCube is a lightweight web application for interactive visualization and exploration of diverse types of genomics data at multiscale resolutions. Especially, HiCube displays synchronized views of Hi-C contact maps and three-dimensional (3D) genome structures with user-friendly annotation and configuration tools, thereby facilitating the study of 3D genome organization and function.

AVAILABILITY AND IMPLEMENTATION: HiCube is implemented in Javascript and can be installed via NPM. The source code is freely available at GitHub (https://github.com/wmalab/HiCube).

SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

PMID:36961339 | DOI:10.1093/bioinformatics/btad154

By Nevin Manimala

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