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Delirium After Traumatic Brain Injury: Prediction by Location and Size of Brain Lesion

Ann Rehabil Med. 2023 Jun 7. doi: 10.5535/arm.23008. Online ahead of print.

ABSTRACT

OBJECTIVE: To examine (1) the location of brain lesion that would predict post-traumatic delirium and (2) the association between volume of brain lesion and occurrence of delirium in patients with traumatic brain injury (TBI).

METHODS: A retrospective study was conducted by reviewing medical records of 68 TBI patients, categorized into two groups: the delirious group (n=38) and non-delirious group (n=30). The location and volume of TBI were investigated with the 3D Slicer software.

RESULTS: The TBI region in the delirious group mainly involved the frontal or temporal lobe (p=0.038). All 36 delirious patients had brain injury on the right side (p=0.046). The volume of hemorrhage in the delirious group was larger by about 95 mL compared to the non-delirious group, but this difference was not statistically significant (p=0.382).

CONCLUSION: Patients with delirium after TBI had significantly different injury site and side, but not lesion size compared to patients without delirium.

PMID:37317796 | DOI:10.5535/arm.23008

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