J Assoc Physicians India. 2024 Aug;72(8):e26-e30. doi: 10.59556/japi.72.0428.
ABSTRACT
INTRODUCTION: Unlike conventional management protocols, like dressings, wound debridement, and skin grafting that do not facilitate healing, platelet-rich plasma (PRP) directly feeds growth factors to enhance wound healing.
MATERIALS AND METHODS: An open randomized controlled trial with a sample size of 60 was carried out on patients with a wound surface area ≤10 × 10 cm2 with 30 participants in each. The PRP group (PRPG) was given autologous PRP using the infiltration technique, and the control group (CG) was treated using conventional dressings.
RESULTS: The PRPG showed a reduction from 1421 to 661 mm2, whereas the CG showed a decrease from 1710 to 1478 mm2 on day 30. The PRP group had a decreased hospital stay (n = 14) in comparison to the CG (n = 17.5 days). The rate of epithelization (mean) is 11.12 mm2/day in the CG and 34.026 mm2/day in the PRPG.
CONCLUSION: Platelet-rich plasma (PRP) can be considered a primary modality for wound management because of decreased length of hospital stay, analgesic effects, fastened rate of healing, and absence of adverse reactions.
PMID:39163067 | DOI:10.59556/japi.72.0428
