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Time to Treatment in Advanced Lung Cancer: A Quality Improvement Project Using Nurse Navigation and Liquid Biopsy

Clin J Oncol Nurs. 2025 Jan 17;29(1):E28-E36. doi: 10.1188/25.CJON.E28-E36.

ABSTRACT

BACKGROUND: Newly diagnosed patients with lung cancer experience significant challenges navigating a fragmented health system. Nurse navigators can use clinical expertise and coordination to address barriers to care.

OBJECTIVES: This quality improvement project aimed to expedite the selection and initiation of first-line treatment for patients with stage III or IV lung cancer. Using a nurse navigator process early on in care, coupled with liquid biopsy, this project focused on reducing the time from tissue biopsy to treatment decision.

METHODS: The team performed a retrospective chart review 12 months preimplementation and 8 months postimplementation.

FINDINGS: Using liquid biopsy, the time to treatment initiation was 21 days compared to 36 days with tissue biopsy only (p = 0.003). Postimplementation, median days to treatment decreased from 34 to 23.5 (p = 0.027), and treatment decisions made during the initial medical oncology visit increased from 38% to 55%.

PMID:39933081 | DOI:10.1188/25.CJON.E28-E36

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