Clin J Oncol Nurs. 2025 Mar 14;29(2):E52-E59. doi: 10.1188/25.CJON.E52-E59.
ABSTRACT
BACKGROUND: Antineoplastic drug (AD) exposure presents severe risks to healthcare workers. Previous studies have demonstrated that patient bathrooms are highly contaminated and have led to concern for excreta as a source of environmental contamination with ADs.
OBJECTIVES: This study assessed AD contamination and current cleaning practices to remove AD surface contamination in patient bathrooms.
METHODS: Three surfaces in the bathrooms of patients who had received etoposide and/or cyclophosphamide were sampled and analyzed for contamination at three time points. Liquid chromatography-tandem mass spectrometry was used for analysis. Interviews and observations of daily and discharge cleaning were conducted to understand cleaning practices.
FINDINGS: A significant reduction in etoposide contamination on toilets and floors was observed following discharge cleaning; however, no significant reduction was observed on walls for either AD or on floors for cyclophosphamide.
PMID:40096556 | DOI:10.1188/25.CJON.E52-E59
