Mymensingh Med J. 2025 Apr;34(2):351-354.
ABSTRACT
Menopause, due to decrease level of estrogen in women between the ages of 45-55 years, is a natural process that is characterized by the complete stoppage of menstrual cycle is called menopause. Because of imbalance of hormone mainly estrogen the efficiency of life is disturbed as a result various postmenopausal syndromes such as irritability, night sweats, vaginal dryness, hot flushes, depression, sleep disturbance and headache can occur in this period. This study was done to evaluate the changes of Body mass index (BMI) and serum uric acid in postmenopausal women in comparison to reproductive women. This analytical type of cross sectional study was carried out in the Department of Physiology, Mymensingh Medical College, Bangladesh from January 2023 to December 2023. A total number of 200 healthy women were enrolled in this study. Among them, one hundred (100) female subjects were taken as control group (Group I) age ranges from 25-45 years and one hundred (100) female subjects were taken as study group (Group II) age ranges from 45-65 years. BMI was calculated by anthropometric measurement such as height and weight was taken in meter and kilogram respectively and serum uric acid is expressed in mg/dl. Output were expressed as mean±SD and by using unpaired students’ ‘t’ test, statistical significance of difference among the group was calculated. The mean±SD of BMI of Group I and Group II were 21.91±1.57 kg/m² and 26.92±2.06 kg/m² respectively. In the study group the mean±SD of BMI is notably increased in study group in comparison with control group. The mean±SD of serum uric acid of Group I and Group II were 4.18±1.33 mg/dl and 7.36±0.46 mg/dl respectively. In the study group the mean±SD of serum uric acid was notably increased in study group in comparison with control group. Postmenopausal women with higher BMI and serum uric acid caused by lower level of female sex hormone specially estrogen hormone increased the change of cardiovascular disease, stroke, chronic renal failure, type-2 diabetes mellitus, insulin resistance and metabolic syndrome. So, the assessment of this parameter is important for early detection and prevention of complication related to higher BMI and serum uric acid for leading a healthy life.
PMID:40160049
