Chem Commun (Camb). 2025 May 23. doi: 10.1039/d5cc00856e. Online ahead of print.
ABSTRACT
Herein, we investigate a two-point crosslinked amyloid-β (Aβ) dimer, which forms an intermolecular β-sheet. The atomic force microscopy statistical results indicate that the heights of these dimers are approximately 0.37 nm, providing a baseline for the Aβ peptide sizes and improving our understanding of Aβ oligomers in Alzheimer’s disease.
PMID:40406894 | DOI:10.1039/d5cc00856e