J Electrocardiol. 2025 Aug 26;93:154097. doi: 10.1016/j.jelectrocard.2025.154097. Online ahead of print.
ABSTRACT
BACKGROUND: Hypertensive crisis (HC) is recognized as a contributing factor in the development of cardiac arrhythmias. This study aims to assess Tp-e interval, Tp-e/QT (TQR), and Tp-e/QTc (TQcR) ratios in patients experiencing hypertensive urgency and emergency, in order to evaluate the potential risk of ventricular arrhythmias.
METHODS: A prospective study was conducted involving HC patients admitted to a tertiary hospital’s emergency department between June 1, 2022, and June 30, 2024. Patients were categorized into three groups: hypertensive emergency, hypertensive urgency, and control group. Data collected included demographic characteristics, vital signs, laboratory results, and electrocardiography (ECG) parameters such as Tp-e interval, TQR, and TQcR.
RESULTS: Among the 235 eligible patients, 57 % were female and 43 % male. The hypertensive urgency group included 130 patients, the emergency group 45, and the control group 60. Statistically significant differences in Tp-e, TQR, and TQcR values were observed across all groups (p < 0.001). These metrics demonstrated moderate positive correlations with both systolic and diastolic blood pressures.
CONCLUSION: Increased Tp-e, TQR, and TQcR values identified in HC patients suggest a heightened risk for ventricular arrhythmias. These findings support the routine evaluation of these ECG.
PMID:40907074 | DOI:10.1016/j.jelectrocard.2025.154097
