Eur Spine J. 2025 Sep 11. doi: 10.1007/s00586-025-09358-y. Online ahead of print.
ABSTRACT
PURPOSE: This study aims to assess the outcomes of combining oblique lumbar interbody fusion (OLIF) with anterolateral screw fixation (ASF) and stress endplate augmentation (SEA) in comparison to OLIF combined with pedicle screw fixation (PSF) for the treatment of degenerative lumbar spinal stenosis (DLSS) in patients with osteoporosis (OP).
METHODS: We performed a retrospective analysis of patients diagnosed with DLSS who underwent OLIF in conjunction with either SEA and ASF (SEA-ASF group) or PSF (PSF group). Clinical outcomes, including the visual analog scale (VAS) scores for lumbar and leg pain, as well as the Oswestry Disability Index (ODI), were assessed at various postoperative intervals and compared to preoperative values. Additionally, radiographic outcomes such as disc height (DH), lumbar lordosis (LL), segmental lordosis (SL), cage subsidence (CS), and fusion rate were evaluated at different postoperative intervals and compared to their preoperative measurements.
RESULTS: A total of 65 patients were enrolled in the study, comprising 30 individuals in the SEA-ASF group and 35 in the PSF group. No statistically significant differences were observed in surgery-related complications between the groups. While VAS and ODI scores did not differ significantly at the 24-month follow-up, the SEA-ASF group exhibited superior scores at both 1 day and 1 month post-surgery (P < 0.05). Significant differences were observed in DH, LL, and SL at both 12 and 24 months postoperatively between the two groups (P < 0.05). At the 24-month postoperative follow-up, the incidence of CS was observed to be 16.67% (5 out of 30) in the SEA-ASF cohort and 11.43% (4 out of 35) in the PSF cohort. Statistical analysis revealed no significant difference between the two groups (P = 0.542). Fusion rates at the 24-month postoperative follow-up were 83.33% (25/30) in the SEA-ASF group and 85.71% (30/35) in the PSF group, also showing no significant difference (P = 0.791).
CONCLUSION: For the management of DLSS patients with osteoporosis, we propose that the integration of OLIF with SEA and ASF constitutes a viable therapeutic option. This approach demonstrates comparable clinical and radiological outcomes to OLIF-PSF, while offering benefits such as reduce operative duration, decrease blood loss, and minimize tissue trauma.
PMID:40931132 | DOI:10.1007/s00586-025-09358-y
