J Cosmet Dermatol. 2025 Dec;24(12):e70556. doi: 10.1111/jocd.70556.
ABSTRACT
BACKGROUND: Regenerating Skin Nectar with TriHex+ Technology (Nectar 2.0; Alastin Skincare Inc., Carlsbad, CA) is a next-generation anhydrous serum reformulated with Octapeptide-45 to improve skin healing and hydration. Clinical trials and case studies assessed the safety, effectiveness, and patient satisfaction of Nectar 2.0 across various aesthetic procedures, including nonablative and ablative laser treatments, as well as microcoring technology.
METHODS: A multimodal clinical approach was used, including a randomized, double-blind, split-face study for nonablative laser procedures, an in-use study assessing skin barrier function and hydration, and case studies for ablative laser and Ellacor microcoring treatments. Investigator and subject assessments, standardized photography, and bioinstrumentation measurements (TEWL and Corneometry) were utilized to evaluate outcomes.
RESULTS: Nectar 2.0 showed superior outcomes in reducing edema and enhancing tactile roughness and fine lines in nonablative laser procedures. In ablative and microcoring treatments, faster healing, less crusting, and decreased exudation were noted, along with higher patient satisfaction compared to the control. Bioinstrumentation confirmed statistically significant improvements in skin barrier recovery and hydration over 14 days. The product was well tolerated.
CONCLUSION: Regenerating Skin Nectar with TriHex+ Technology Serum (Alastin Skincare Inc., Carlsbad, CA) has proven to be a safe and effective periprocedural skincare solution that enhances healing, improves skin quality, and increases patient satisfaction across various aesthetic procedures. Its benefits are especially significant in deeper treatments, supporting its widespread use in clinical practice.
PMID:41293824 | DOI:10.1111/jocd.70556
