Int J Womens Health. 2025 Nov 20;17:4705-4715. doi: 10.2147/IJWH.S537210. eCollection 2025.
ABSTRACT
This study aimed to analyze the changes in quality of life (QOL) and emotional well-being of patients undergoing diathermy ablation for cervical intraepithelial neoplasia 2/3 (CIN). A total of 40 patients were recruited for a prospective clinical trial, and the European Organization of Research and Treatment for Cancer (EORTC)-QLQ-C30 and EORTC-QLQ-CX24 questionnaires were used to assess QOL before surgery and at 3 and 6 months postoperatively. Friedman and Wilcoxon tests were employed for statistical analysis. The results showed significant improvements in emotional functioning, body image, symptom experience, and physical functioning after surgery. Vaginal discharge and abnormal bleeding decreased over time, indicating improved symptom control. Sexual activity was temporarily affected but eventually returned to preoperative levels at 6 months after surgery. This study highlights the positive impact of diathermy ablation on psychological well-being and QOL, and emphasizes the importance of patient-centered care in CIN treatment. These survey questionnaires will eventually enable us to compare global QOL assessments between patients undergoing various cervical cancer treatments, such as trachelectomy, and those with precancerous lesions.
PMID:41293763 | PMC:PMC12642790 | DOI:10.2147/IJWH.S537210
