Georgian Med News. 2025 Oct;(367):176-180.
ABSTRACT
BACKGROUND: Tracheoesophageal fistula with esophageal atresia (TEF/EA) is a rare congenital disease which has high morbidity and complications. However, there are various factors which can increase the risk of mortality among TEF/EA patients.
AIM: The study’s objective was to assess the features and results of treatment for patients with tracheoesophageal fistula (TEF) and esophageal atresia. Another goal of the study was to evaluate and determine how related anomalies and syndromes affected the course of treatment.
SETTING & DESIGN: a retrospectively designed study was conducted at the Maternity and Children’s Hospital in Qassim, Saudi Arabia.
METHOD & MATERIALS: Patients underwent surgical treatment for TEF/EA were included in the study. Electronic records were used to extract the data. Hence, all the data for all required variables were extracted on excel sheet.
STATISTICAL ANALYSIS USED: a statistical package of social sciences (SPSS) was used. Median, Interquartile range (IQR) and frequency distributions were tabulated as a part of descriptive analysis of the data. For the inferential analysis, chi-square test and odds ratios were computed. All P-values less than .05 were considered statistically significant.
RESULTS: Findings of the study revealed that the presence of associated anomalies (p=.003) and associated syndromes (p=.016) was significantly correlated with non-survival. In addition, associated anomalies were present in all non-survivors (P=.003), and associated syndrome was detected in 3 out of 4 non-survivors (P=.016).
CONCLUSION: The mortality rate was found to be strongly correlated with certain demographic variables, such as birth weight and gender. Furthermore, compared to their counterparts, patients with multiple anomalies and related syndromes had a higher death rate.
PMID:41370701
