PLoS One. 2026 Jan 27;21(1):e0341187. doi: 10.1371/journal.pone.0341187. eCollection 2026.
ABSTRACT
Hospital readmissions prolong patient suffering and increase healthcare expenditures. Unplanned readmission rates, such as those reported by the Center for Medicare & Medicaid Services (CMS), distinguish between planned and unplanned readmissions. However, within unplanned readmissions, there is no distinction between those that are preventable versus unpreventable by the hospitals. Alternative approaches attempting to identify potentially preventable readmissions directly from coded medical data have been explored but have shown low sensitivity. Consequently, identifying preventable readmissions remains a time-consuming task for hospital quality managers seeking to allocate improvement resources effectively. To address this challenge, we aimed to develop and evaluate a probabilistic approach to improve the identification of preventable readmissions among unplanned readmissions. Using a retrospective record review of 600 single inpatient stays from a tertiary referral hospital group in Switzerland, we investigated the hypothesis that readmitted patients with a low expected probability for readmission (based on a logistic regression model using patient characteristics) would retrospectively show higher odds of having experienced a potentially or most likely preventable readmission (as assessed by the reviewers). The results confirmed our hypothesis: patients in the third with the lowest expected probability of readmission (compared with those in the highest third) had 6.6 and 8.7 times higher odds, respectively, of having experienced a potentially or most likely preventable readmission. Among preventable readmissions, the leading causes of readmission were surgical complications, medication-related reasons, nonsurgical complications, and premature discharge. Our proposed probabilistic approach can be used by hospital quality managers to focus case finding efforts on unexpectedly readmitted patients and aid effective resource allocation for improvement initiatives.
PMID:41592101 | DOI:10.1371/journal.pone.0341187
