J Occup Environ Med. 2026 Mar 6. doi: 10.1097/JOM.0000000000003694. Online ahead of print.
ABSTRACT
OBJECTIVE: To assess the global burden and trends of ischemic heart disease (IHD) attributable to non-optimal temperature among younger and older populations using Global Burden of Disease 2021 data.
METHODS: We estimated temperature-attributable IHD burden (high, low, non-optimal) from 1990-2021 using deaths, Disability-adjusted life years (DALYs), age-standardized rates, and joinpoint regression, stratified by age, sex, region, and Socio-demographic Index. Decomposition analysis examined demographic contributions.
RESULTS: From 1990-2021, age-standardized mortality and disability rates declined globally, yet absolute numbers of deaths and DALYs, especially in older adults. The burden from low temperatures was disproportionately higher in older adults, with extreme disparities in Central Asia. Sex differences shifted with age, and burdens were consistently higher in lower SDI regions.
CONCLUSIONS: Older adults bear a substantially greater IHD burden attributable to non-optimal temperature, highlighting the need for targeted prevention strategies.
PMID:41801250 | DOI:10.1097/JOM.0000000000003694
