J Invest Surg. 2026 Dec;39(1):2586017. doi: 10.1080/08941939.2025.2586017. Epub 2026 Mar 9.
ABSTRACT
BACKGROUND: Postoperative sore throat (POST) is an distressing complication following endotracheal intubation, particularly with double-lumen tube (DLT) intubation. Study evaluated the effects of two local anesthetic techniques on hemodynamic responses and POST in DLT-intubated patients.
METHODS: A randomized controlled study was conducted with 60 patients scheduled for elective thoracic surgery. Participants were randomized into three groups: TrachoSpray group (2 mL of 10% lidocaine), Manual spray group (10% lidocaine) and, Control group (0.9% saline). Hemodynamic parameters, including systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP), were monitored preoperatively, intraoperatively, and postoperatively. POST was assessed using a visual analog scale at 2, 6, 12, and 24 h post-extubation.
RESULTS: Both lidocaine groups demonstrated significant reductions in SBP, DBP, and MAP at key time points compared to control group. Post-extubation, MAP was significantly higher in TrachoSpray group than lidocaine group (p = 0.04). No statistically significant differences in POST scores were observed between groups.
CONCLUSIONS: TrachoSpray device and manual lidocaine spray improved hemodynamic stability in DLT-intubated patients; however, neither method resulted in a significant reduction in POST scores. Further research is needed to confirm these hemodynamic benefits and to explore potential effects on long-term outcomes.
PMID:41797600 | DOI:10.1080/08941939.2025.2586017
