Plast Reconstr Surg. 2026 Mar 11. doi: 10.1097/PRS.0000000000013017. Online ahead of print.
ABSTRACT
OBJECTIVE: Aim of this study is to evaluate the effectiveness of stromal vascular fraction (SVF) and nano-fat applications on photoaging and skin quality in the facial region, as well as their possible superiority over each other.
MATERIALS AND METHODS: Study was conducted on 20 volunteer patients aged 40-55 who applied to City Hospital Plastic Reconstructive and Aesthetic Surgery outpatient clinic between April-July 2024 with complaints of facial aging and skin complaints in facial area. After initial evaluation, patients were divided into two groups; SVF was injected into the facial region of 10 patients, and nano-fat was injected into facial region of the other 10 patients. Preoperative, postoperative 1st and 3rd month skin evaluations of the patients were made with the visa skin analysis system, and dermis thicknesses were measured with high-frequency ultrasound (HFU). The data obtained prospectively were statistically analyzed.
RESULTS: In the visia skin evaluations of the patients, it was observed that SVF and nano-fat injection reduced wrinkle scores significantly (p<0.05). Also, SVF injection reduced ultraviolet (UV) damage, red area and porphyrin score significantly (p<0.05). No significant dermis change was detected in the dermis thickness measurement performed with HFU preoperatively and postoperatively.
CONCLUSION: It was observed that SVF and nano-fat injections were effective on wrinkles and both applications were valuable in anti-aging treatments. SVF application was effective in reducing UV damage, vascular pathologies and inflammation. So, it can be said that SVF applications are useful treatment methods in reducing photoaging and improving skin quality.
PMID:41811159 | DOI:10.1097/PRS.0000000000013017
