Nature. 2026 Apr;652(8108):143-150. doi: 10.1038/s41586-025-10078-y. Epub 2026 Apr 1.
ABSTRACT
Pursuing replicability – independent evidence for previous claims – is important for creating generalizable knowledge1,2. Here we attempted replications of 274 claims of positive results from 164 quantitative papers published from 2009 to 2018 in 54 journals in the social and behavioural sciences. Replications were high powered on average to detect the original effect size (median of 99.6%), used original materials when relevant and available, and were peer reviewed in advance through a standardized internal protocol. Replications showed statistically significant results in the original pattern for 151 of 274 claims (55.1% (95% confidence interval (CI) 49.2-60.9%)) and for 80.8 of 164 papers (49.3% (95% CI 43.8-54.7%)), weighed for replicating multiple claims per paper. We observed modest variation in replication rates across disciplines (42.5-63.1%), although some estimates had high uncertainty. The median Pearson’s r effect size was 0.25 (95% CI 0.21-0.27) for original studies and 0.10 (95% CI 0.09-0.13) for replication studies, an 82.4% (95% CI 67.8-88.2%) reduction in shared variance. Thirteen methods for evaluating replication success provided estimates ranging from 28.6% to 74.8% (median of 49.3%). Some decline in effect size and significance is expected based on power to detect original effects and regression to the mean because we replicated only positive results. We observe that challenges for replicability extend across social-behavioural sciences, illustrating the importance of identifying conditions that promote or inhibit replicability3,4.
PMID:41922700 | DOI:10.1038/s41586-025-10078-y
