Phytother Res. 2026 Apr 6. doi: 10.1002/ptr.70321. Online ahead of print.
ABSTRACT
Most Germans consider herbal medicinal products (HMPs) to be an important supplement to conventional medicine. Despite existing clinical evidence for safety and efficacy, they are still not sufficiently integrated into drug therapy of gynaecological complaints in everyday practice. By analysing patient-reported outcomes (PROs), this gap in medical care can be closed. Real-world data was extracted from the pharmaco-epidemiological database PhytoVIS. We analysed a sample (n = 1658) containing PROs from women who utilised HMPs to treat their gynaecological complaints applying descriptive and non-parametric bivariate statistical tests. Perceived effectiveness and tolerability of HMPs was rated as very good. For the treatment of menstrual complaints, Vitex agnus-castus L. was primarily used, and Actaea racemosa L. for menopausal complaints. Various herbal drugs were applied for uncomplicated urinary tract infections (uUTIs), but mainly Arctostaphylos uva-ursi (L.) Spreng. Regarding the pharmaceutical form, herbal teas were preferred for the treatment of uUTIs or by very young or elderly women. All other pharmaceutical forms were favoured for menstrual and menopausal complaints or middle-aged women. The pharmaceutical form did not impact the perceived therapeutic effectiveness. Our results provide valuable insights into patient preferences and show options for their integration into existing treatment strategies. By identifying the most popular and efficacious plants for certain gynaecological ailments, we support healthcare providers to better address the growing demand for complementary treatment options. This knowledge helps in tailoring healthcare to meet patient needs and to ensure the safety and efficacy of HMPs.
PMID:41937616 | DOI:10.1002/ptr.70321
