J Investig Med. 2026 Apr 10:10815589261444738. doi: 10.1177/10815589261444738. Online ahead of print.
ABSTRACT
BACKGROUND: In clinical practice, effectively managing agitation and hemodynamic stability during general anesthesia awakening remains challenging, despite their importance for patient safety and recovery.
PURPOSE: This study aimed to expound the effect of dexmedetomidine combined with anesthesia awakening nursing on agitation and hemodynamics in patients under general anesthesia during awakening period.
STUDY TYPE: A prospective studyPopulation: Ninety patients who underwent general anesthesia surgery were selected and divided into a control group (dexmedetomidine+routine nursing care) and an intervention group (dexmedetomidine+anesthesia awakening nursing), with 45 cases in each group.Assessment technique(s) or outcome(s):The post-anesthesia recovery room stay and awakening time, VAS score, the occurrence of agitation during the awakening period, and incidence of adverse reactions were compared.
STATISTICAL TESTS: Categorical data were expressed as rates or percentages; measurement data were expressed as mean ± standard deviation. Differences were significant at P < 0.05 (two-sided).
RESULTS: Intervention group patients had shorter recovery room stay (29.98±6.88 vs. 37.78±6.58 min) and recovery time (8.52±0.99 vs. 10.62±0.99 min) versus controls (P<0.05). VAS scores were lower at 2 hours (4.53±0.63 vs. 5.58±0.54) and 6 hours post-surgery (2.47±0.69 vs. 4.49±0.51). Anesthesia recovery agitation (13.33% vs. 37.78%) and postoperative adverse reactions (11.11% vs. 44.44%) were reduced (all P<0.05).
DATA CONCLUSION: Dexmedetomidine combined with anesthesia awakening care can enhance sedation scores, reduce pain levels, and have a minimal impact on patients’ hemodynamics, ultimately improving the quality of awakening. This approach also leads to higher patient satisfaction with care, making it a promising option for clinical promotion and application.
PMID:41964271 | DOI:10.1177/10815589261444738
