Clin Exp Dent Res. 2026 Apr;12(2):e70352. doi: 10.1002/cre2.70352.
ABSTRACT
OBJECTIVES: Type 2 diabetes mellitus (T2DM) is a major systemic disease, predisposing patients to inflammatory conditions, and it is considered a grade modifier of periodontitis. However, its association with peri-implant diseases is still under investigation. This study aimed to investigate the possible association between diabetes and peri-implant disease.
MATERIAL AND METHODS: Seventy patients (35 with T2DM and 35 non-diabetic) were included, for a total of 227 dental implants in function for at least 1 year. Patient characteristics, implant features, and peri-implant diseases (including peri-implant mucositis and peri-implantitis) were recorded.
RESULTS: The overall prevalence of peri-implant diseases was not statistically different between diabetic and non-diabetic subjects (80% vs. 77%, p = 0.99). When distinguishing between peri-implant mucositis and peri-implantitis, the prevalence of peri-implant mucositis (51% in diabetic patients vs. 63% in non-diabetic individuals; p = 0.47) and peri-implantitis (51% in diabetic patients vs. 43% in non-diabetic individuals; p = 0.63) did not differ significantly between the two groups.
CONCLUSIONS: Our findings did not suggest different occurrence of peri-implant mucositis and peri-implantitis in diabetic and non-diabetic subjects. Therefore, type 2 diabetes may not play a relevant role in peri-implant diseases.
PMID:42035463 | DOI:10.1002/cre2.70352
