J Int Med Res. 2026 Jun;54(6):3000605261462010. doi: 10.1177/03000605261462010. Epub 2026 Jun 27.
ABSTRACT
ObjectiveTo evaluate the efficacy of small-incision, point-by-point debridement combined with double-cannula negative-pressure irrigation and drainage in the treatment of granulomatous mastitis.MethodsThis single-center, retrospective matched cohort study included 118 patients with granulomatous mastitis who were treated at the Third People’s Hospital of Mianyang between January 2022 and December 2024. Patients with comparable clinical characteristics were matched in a 1:1 ratio and assigned to either the treatment or control group, with 59 patients in each group. Patients in the treatment group underwent small-incision, point-by-point debridement of necrotic tissue combined with double-cannula continuous negative-pressure irrigation and drainage, whereas those in the control group underwent conventional incision and drainage combined with negative-pressure drainage. Postoperative drainage volume, time to drain removal, frequency of dressing changes, wound healing time, primary healing rate, recurrence rate, and breast shape score were compared between the two groups.ResultsCompared with the control group, the treatment group had a significantly lower postoperative drainage volume, fewer dressing changes, shorter time to drain removal, and shorter wound healing time. The recurrence rate was significantly lower in the treatment group than in the control group (χ2 = 5.221, p < 0.05). The primary healing rate was significantly higher in the treatment group than in the control group (χ2 = 4.140, p < 0.05). In addition, breast shape scores were significantly higher in the treatment group. All between-group differences were statistically significant.ConclusionSmall-incision, point-by-point debridement combined with double-cannula negative-pressure irrigation and drainage may promote wound recovery, reduce recurrence, and better preserve breast appearance in selected patients with granulomatous mastitis requiring surgical treatment. Further prospective studies are warranted to confirm these findings.
PMID:42363797 | DOI:10.1177/03000605261462010
