PLoS One. 2026 Aug 11;21(8):e0354367. doi: 10.1371/journal.pone.0354367. eCollection 2026.
ABSTRACT
The non-medical use of sedatives and prescription opioids is a growing public health concern, particularly among Latino populations. This study aim was to identify individual and social determinants associated with non-medical use of sedatives and prescription opioids among Latinos in the United States. A cross-sectional analysis was conducted using the National Institute of Health All of Us Dataset. The sample included 22,457 Hispanic/Latino adults with complete data. The main outcomes were lifetime street opioids use, and past 3-month non-medical use of sedatives and prescription opioids. Independent variables included depression, discrimination, education, income, nativity, and language spoken at home. The non-medical use of sedatives and opioids in the past 3 months was low (0.4% sedatives, 0.2% opioids). Older age, being male, and reporting depression, discrimination, and neighborhood disorder were associated with increased odds of opioids use. Higher education, income, foreign-born status, and non-English language spoken at home were protective factors. Findings highlight the need for culturally tailored interventions targeting high-risk adult Latino subgroups to address opioid and non-medical use of sedatives disparities.
PMID:42579686 | DOI:10.1371/journal.pone.0354367
