Chem Biodivers. 2022 Feb 25. doi: 10.1002/cbdv.202100962. Online ahead of print.
ABSTRACT
One new phenylpropanoid schineolignin D ( 1 ), one new sesquiterpene (-)-(7 S ,10 S )-3,11,12, 13-tetrahydroxycalamenene ( 2 ), one new quinic acid 4-( E )-O-coumaroylquinic acid ethyl ester ( 3 ), and seven known compounds ( 4-10 ) were isolated from the roots of Schisandra chinensis . Their chemical structures were characterized by NMR spectroscopic analyses. All compounds were assessed for their neuroprotective effects on PC12 cell lines induced by H 2 O 2 . The results suggested that compounds 1, 3-4 and 7 exhibited statistically significant neuroprotective activities with the negative control group at 12.5μM.
PMID:35218144 | DOI:10.1002/cbdv.202100962
