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Nevin Manimala Statistics

Genetic variation of 17 autosomal STR loci in the Lahu population from Yunnan and phylogenetic structure exploration among 28 populations

Leg Med (Tokyo). 2022 Feb 25;56:102050. doi: 10.1016/j.legalmed.2022.102050. Online ahead of print.

ABSTRACT

This study evaluated the genetic variation of 17 autosomal short tandem repeat (STR) loci included in the PowerPlex® 18D Kit. Samples of 562 unrelated healthy Lahu individuals living in Yunnan Province in southwestern China were investigated. The data were analyzed to provide information on allele frequencies and other statistical parameters relevant to the forensic population. Of the 17 loci, 16 reached the Hardy-Weinberg equilibrium after Bonferroni correction. A total of 176 alleles were identified in 17 STR loci, and allele frequencies ranged from 0.000890 to 0.578292. The combined discrimination power (CPD) and probability of excluding paternity (CPE) of the 17 STR loci were 0.999999999999999999489 and 0.999998301753122. The genetic relationships among 28 populations were also estimated.

PMID:35240543 | DOI:10.1016/j.legalmed.2022.102050

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