Int J Clin Pract. 2021 Apr 29:e14276. doi: 10.1111/ijcp.14276. Online ahead of print.
ABSTRACT
OBJECTIVES: Helicobacter pylori is a major cause of gastritis and a potential trigger of inflammatory disease. The effect of Helicobacter pylori infection on distal femoral cartilage has yet to be evaluated. The aim of this study was to evaluate femoral cartilage thickness in patients with helicobacter pylori infection and whether Helicobacter pylori infection affects femoral cartilage thickness.
METHODS: This cross-sectional study included 199 patients. To measure the thickness of femoral articular cartilage, 99 patients with Helicobacter pylori infections and 100 Helicobacter pylori negative controls were enrolled into two groups. The measurements were made using a linear probe ultrasonography with the patients in supine positions and their knees in maximum flexion. Demographic, clinical, endoscopic, and laboratory data were collected for all patients.
RESULTS: Both the right and left medial femoral condyles had thinner cartilage thickness in the Helicobacter pylori positive group than in the Helicobacter pylori negative group (p=0.016, p=0.036). For the intercondylar area and lateral femoral condyles, although the Helicobacter pylori positive patients had thinner femoral cartilage thickness than the Helicobacter pylori negative individuals for both extremities, this finding was not statistically significant (p>0.05).
CONCLUSION: Femoral cartilage was thinner in patients with Helicobacter pylori than patients without Helicobacter pylori for right and left medial femoral condyles. This study suggests that Helicobacter pylori infections may affect femoral cartilage thickness and potentially increase the risk of cartilage degeneration.
PMID:33914992 | DOI:10.1111/ijcp.14276
