J Dig Dis. 2023 Jun 16. doi: 10.1111/1751-2980.13200. Online ahead of print.
ABSTRACT
AIM: The objective of this current research is to investigate the association between gastrointestinal ultrasound (GIUS) and capsule endoscopy (CE) in assessing the disease activity in patients diagnosed with Crohn’s disease affecting the small intestine.
METHODS: Retrospective data was gathered on 74 patients, including 50 males and 24 females, with Crohn’s disease affecting the small intestine, who were treated at our hospital between January 2020 and March 2022. Within a week, all patients underwent both GIUS and CE. To assess disease activity and compare GIUS and CE, we used Simple Ultrasound Scoring of Crohn’s Disease (SUS-CD) and Lewis Score (LS), respectively. We considered P < 0.05 as statistically significant.
RESULTS: The results of our study revealed that the SUS-CD had an area under the curve (AUC) of 0.90 (95% confidence interval) with P<0.05, as determined by the ROC analysis. Moreover, the diagnostic accuracy of gastrointestinal ultrasound (GIUS) was 79.7%, with a sensitivity of 93.6%, and a specificity of 81.8% (P<0.05). GIUS exhibited a positive predictive value of 96.7%, a negative predictive value of 69.2%, and a confidence interval of 95% (P<0.05) in predicting CE disease. Furthermore, the agreement between GIUS and CE was assessed using Spearman’s Correlation and SUS-CD with Lewis score (r = 0.82, P < 0.05.) CONCLUSION: To conclude, our findings demonstrate a strong correlation between gastrointestinal ultrasound and capsule endoscopy in assessing the disease activity in patients with Crohn’s disease affecting the small intestine.
PMID:37327014 | DOI:10.1111/1751-2980.13200
