Pediatr Transplant. 2025 May;29(3):e70058. doi: 10.1111/petr.70058.
ABSTRACT
BACKGROUND: Toxoplasma gondii can cause opportunistic infections leading to life-threatening disseminated disease after organ transplantation. However, there is a paucity of pediatric-specific data to guide recommendations for the prevention of toxoplasmosis after solid organ transplantation.
METHODS: To assess current practices, international pediatric transplant providers were surveyed.
RESULTS: Considerable variability in both screening and prophylaxis strategies was found across centers and organ types, with heart transplant programs performing more screening and prophylaxis. Trimethoprim/sulfamethoxazole was the preferred prophylaxis agent for each graft; no toxoplasmosis cases were recalled while patients received prophylaxis.
CONCLUSION: More research is needed to clarify and standardize the optimal toxoplasmosis prevention strategy.
PMID:40025782 | DOI:10.1111/petr.70058
