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Efficacy of Cognitive Behavioural Therapy in Controlling Negative Symptoms in Schizophrenic Patients: A Systematic Review and Meta-Analysis

Int J Psychol. 2025 Jun;60(3):e70045. doi: 10.1002/ijop.70045.

ABSTRACT

The aim of this meta-analysis was to assess the effectiveness of cognitive behavioural therapy (CBT) in reducing negative symptoms in patients with schizophrenia. The search period was from the beginning of the database creation to 30 September 2022. An initial search of 169 articles was conducted through database searches and other means. After applying inclusion and exclusion criteria, seven randomised controlled studies were included in the final analysis. The intervention group included a total of 293 patients with schizophrenia, and the control group included 291 patients with schizophrenia. Meta-analysis showed that there was a statistically significant difference in negative symptom reduction between the CBT intervention group [SMD = -0.26,95% CI (-0.45, -0.07), p = 0.006] and the control group. We analysed the effectiveness of CBT based on previous studies and found that CBT was effective in improving negative symptoms in patients with schizophrenia.

PMID:40194927 | DOI:10.1002/ijop.70045

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